|Family||Gonzalo - Husband (Deceased)|
|First Appearance||"Party With the Zeros"|
|Last Appearance||"All Good Things Must Come to an End"|
|Series lifespan||"Party With the Zeros" to "All Good Things Must Come to an End"|
La Reina, also referred to as "the Queen of the Dead", is first seen in episode 12 of Season 2, "Party With the Zeros" . She had inherited the leadership position of the Zeros drug cartel from her deceased husband Gonzalo. Throughout season 2, she and her gang attempt to hunt down "The Murphy" so she can control a cure made by the captured Dr. Kurian, who is now her servant. She dreams of restructuring the world and creating a new world order with her in charge. After Warren appears to save her from an assassination attempt, she offers Warren a place in her regime and even starts calling her "hermana", meaning sister.
La Reina was married to Gonzalo, who was the leader of the Zeros drug cartel.